Author

Ting-Yu Wang

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Open access Dec 2025

Ultrasonic Reporter of Kinase Activity

Protein kinases are an essential class of enzymes that regulate cellular signaling pathways, with their dysregulation implicated in pathologies such as cancer and neurodegenerative diseases. Despite the existence of high-performance fluorescent biosensors of kinase activity, it remains challenging to study the function...

Jee Won Yang, Zhi-Yang Jin, Ting-Yu Wang et al. · bioRxiv · 0 citations

Open access Aug 2026

FAM136A is an essential chaperone for mitochondrial membrane protein biogenesis

It is concluded that FAM136A is an IMS-resident chaperone, necessary and sufficient to maintain nascent membrane proteins in a folding-competent state to mediate their integration into the bilayer.

M. Ernst, Jichen Zhang, Haoqi Xu et al. · bioRxiv · 0 citations