Author

Ting Zhang

2 papers indexed here

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Review Open access Aug 2026

Gut microbiota-derived metabolites and IL-22 signaling in inflammatory bowel disease: context-dependent regulation of mucosal repair and inflammation

Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis (UC), arises from complex interactions among host susceptibility, microbial dysbiosis, altered metabolite profiles, and dysregulated mucosal immune responses. Interleukin-22 (IL-22), a cytokine that acts primarily on non-hematopoie...

Pei-Xin Shi, Xi-Yuan He, Ling Zhao et al. · Frontiers in Immunology · 0 citations

Oct 2026

Dehydrocostus lactone attenuates sepsis-associated neuroinflammation by directly targeting JAK2 identified through thermal proteome profiling.

Sepsis-associated encephalopathy (SAE) is a severe neurological complication of sepsis characterized by uncontrolled neuroinflammation. Dehydrocostus lactone (DL), a bioactive sesquiterpene lactone derived from Aucklandia lappa Decne., exhibits anti-inflammatory properties; however, its molecular targets in SAE remain...

Xue-Ling He, Ting Zhang, Xue-Ting Chen et al. · Biochemical Pharmacology · 0 citations