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Open access Sep 2026

Complement C3 is associated with cancer-induced frailty: genetic and clinical evidence

Frailty is a degenerative geriatric syndrome characterized by declining muscle mass and function, unintentional weight loss, and fatigue. It is a key risk factor for many geriatric diseases and poor postoperative outcomes. Currently, pathogenesis remains unclear, and apart from nutritional support and exercise, no...

Chao-Bao Zhang, Ting Zhao, Wei-Yi Li et al. · 0 citations
Open access Jul 2026

Low bone mineral density and handgrip strength are associated with increased risk of all-cause mortality: A cohort study with primary analysis and replication in 16,282 adults.

This study aimed to evaluate the modifying effects and joint associations of handgrip strength (HGS) and bone mineral density (BMD) with all-cause mortality, with an exploratory analysis of cardiovascular disease (CVD) mortality. A primary analysis cohort ( n = 11150) and a replication cohort ( n = 5952) were included....

Xin-Yi Huang, Ning-Li Han, Kai Ling et al. · 0 citations

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