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Author

Tingting Liu

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Open access Sep 2026

mRNA-encoding CD19-targeting T cell engager for refractory immune thrombocytopenia.

While T cell engagers (TCEs) and chimeric antigen receptor (CAR)-T cell therapy show clinical promise for B cell depletion, challenges regarding safety, efficacy, and durability persist. ABO2203 is a lipid nanoparticle-formulated messenger RNA (mRNA) encoding a CD19-targeting TCE. In transgenic mice, ABO2203 induced co...

Meng-Yan Wang, Ting-Ting Liu, Qi Dai et al. · 0 citations

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