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Author

Titto Varughese

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Open access Oct 2026

Structure-guided Discovery of a Computationally Prioritized Candidate for MMP-13 Inhibition with Favorable Drug-likeness

Collagenases, a subgroup of matrix metalloproteinases (MMPs), contribute to pathological angiogenesis by degrading extracellular matrix components, and their dysregulation is closely linked to tumor invasion and metastasis. This study aimed to identify potential collagenase inhibitors through an integrated computationa...

Doono Mariya, Deepthy Varghese, Titto Varughese et al. · 0 citations

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