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Tobias Straub

1 paper indexed here

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Open access Aug 2026

Pre-treatment T cell features and immune-milieu characteristics shape treatment-induced exhaustion and resistance to Blinatumomab in B-cell acute lymphoblastic leukemia

Background Blinatumomab (Blina), a CD19×CD3 bispecific T cell engager, is approved for the treatment of B-cell precursor acute lymphoblastic leukemia (BCP-ALL), yet resistance remains a major challenge and the mechanisms driving treatment failure remain poorly understood. Methods To define the immunological determinant...

Francesco Corrado, V. Blumenberg, Maryam Kazerani et al. · 0 citations

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