Jul 2026
Knockdown of XRCC5 and XRCC6 activity using CRISPR/Cas9 technology enhances homology-directed DNA repair at the CHST6 locus in HEK293 cells.
In vitro editing of exon 3 of CHST6 using CRISPR/Cas9 in human embryonic kidney cells suggests that targeting NHEJ to enhance HR may represent a promising therapeutic strategy for MCD.
Aparajita Baruah, Tobias Wimmer, K. Stieger et al.
· Experimental Eye Research · 0 citations