Targeting interrelated NLRP3 and NF-κβ signaling pathways to develop enhanced tolerogenic dendritic cells: Promising prospect for autoimmune disorders.
Proper immune response needs a regulated interaction between adaptive and innate immunity and dendritic cells (DCs) as professional antigen presenting cells coordinate their interaction. In order to maintain the balance between tolerance and initiation of immune response, these DCs should be activated in a regulated ma...