Open access
Sep 2026
PAX3-SIX2 muscle stem cell heterogeneity drives muscle-specific repair dynamics diversification
The human body contains around 640 distinct muscles, each capable of regeneration following injury through the action of muscle-specific stem cells (MuSCs), that express the transcription factor PAX7. Its paralog, PAX3, a master regulator of embryonic myogenesis, is selectively expressed in a subset of adult quiescent...
Virginia Zoglio, Sarah Chebouti, Fayez Issa et al.
· Science Advances · 0 citations