ABSTRACT Owing to the intrinsic instability of mRNA, its routes of administration are limited, and to date, only injectable delivery has been clinically applied. In contrast, oral administration exposes mRNA to a variety of substances in the gastrointestinal (GI) tract. Despite these challenges, oral delivery remains t...
Toma Shinkai, Koki Ogawa, Mohamed S. Mohamed et al.· Drug development research (P...· 0 citations
Although photodynamic therapy (PDT) and photothermal therapy (PTT) offer minimally invasive treatment modalities, their clinical applications remain limited by poor tumor accumulation of photoactive agents and restricted light penetration. Iron-platinum nanoparticles (FePtNPs) have attracted considerable attention as p...
Rin Yamashita, Koki Ogawa, Kazuki Sato et al.· International journal of pha...· 0 citations
Recently, lipid bilayer nanoparticles, similar to extracellular vesicles, have been identified in various plant juices and extracts. These plant-derived nanoparticles have attracted attention in the medical field for their intrinsic anti-inflammatory and antioxidant properties and for the advantages of inexpensive and...
Susumu Suwabe, Koki Ogawa, Toma Shinkai et al.· Biological and Pharmaceutica...· 0 citations
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