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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Tomonori Ito

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Sep 2026

Structural optimization of 2-(2-aminopyridin-4-yl)-N-(3-carbamoyl-1H-pyrazol-4-yl)-1,3-oxazole-4-carboxamide derivatives as potent interleukin-1 receptor-associated kinase 4 inhibitors.

Interleukin-1 receptor-associated kinase 4 (IRAK4) is an essential component in signaling pathways downstream of Toll-like receptor/interleukin (IL)-1 receptor and has attracted much interest as a therapeutic target for a wide range of inflammatory and autoimmune diseases as well as cancers. In our efforts to enhance t...

H. Inami, Junko Watanabe, Naohiro Aoyama et al. · 0 citations

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