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Open access 2026

IL-23 promotes PD-L1 expression and tumor immune evasion via METTL16 pathway.

Interleukin-23 (IL-23) is a pivotal cytokine implicated in tumor progression and immune evasion, yet its precise molecular mechanisms remain incompletely characterized. In this study, we elucidate that IL-23 upregulates METTL16, which in turn enhances PD-L1 expression and facilitates tumor immune escape. Integrated ana...

Xue-Shan Pan, Yue Wang, Jing-Jing Luo et al. · 1 citation

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