Open access
Jul 2026
An Integrated Transcriptional and Post-Transcriptional Regulatory Circuit Orchestrated by NUDT21 Maintains the Proliferation and Survival of Neuroblastoma.
BACKGROUND Neuroblastoma (NB) is the most prevalent pediatric solid tumor, associated with a poor prognosis. While alternative polyadenylation (APA) is a key post-transcriptional regulatory mechanism in many cancers, its role in NB remains largely unexplored. METHODS We used public expression profiles from NB and nor...
Yang Yang, Chunxia Shi, Jian-Wei Wang et al.
· Neuro-Oncology · 0 citations