Author

Tony Chen

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Sep 2026

SPLENDID incorporates continuous genetic ancestry in biobank-scale data to improve polygenic risk prediction across diverse populations.

It is shown that SPLENDID significantly improved prediction accuracy over existing methods, particularly for non-European and admixed ancestries, particularly for non-European and admixed ancestries.

Tony Chen, Hao-Yu Zhang, Rahul Mazumder et al. · Nature Methods · 0 citations