Sep 2026
Abstract A061: Spatial Whole-Transcriptome Profiling Reveals Immune-Suppressive Stromal Niches and Associated Ductal Tumor Cell-State Programs in Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is characterized by marked spatial heterogeneity and a highly variable immune microenvironment, ranging from myeloid-enriched, immune-suppressive regions to more immune-responsive niches. How tumor epithelial and stromal compartments contribute to these spatial immune states, a...
Yuan Sui, Jonathan R. Weitz, Jessica Bruning et al.
· Cancer Research · 0 citations