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Author

Tooki Chu

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Open access

B-Cell Aware Analysis of Single-Cell Transcriptomics Data.

A protocol is presented that analyses scRNA-seq alignments and count matrices, as well as B-cell receptor sequencing data obtained in parallel to scRNA-seq, and provides practical guidance on how CSR and SHM information can be extracted from the data and utilized to build robust computational models of B-cell maturatio...

Joseph C. F. Ng, R. Ruiz-Hernandez, I. Withnell et al. · 0 citations
Open access Jul 2026

Spatial ecology of breast cancer reveals co-evolution of proliferative and dormant niches.

A G0 persister-like state with reduced copy number alteration burden and hallmarks of dormancy is uncovered, characterised by transcriptional reprogramming of stress response pathways and increased epithelial-mesenchymal plasticity.

Cenk Celik, William A. Weston, Thais de Moraes-Lacerda et al. · 1 citation

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