Open access
Oct 2026
Spatial transcriptomics reveals early immune responses in HIV and tuberculosis coinfection in humanized mice
Mycobacterium tuberculosis (Mtb) and human immunodeficiency virus (HIV) coinfection is a major public health concern, yet early immune and tissue changes during coinfection remain incompletely understood. Here we show, using a humanized mouse model and spatial transcriptomics of lung tissue, that early immune cell...
S. Adduri, J. Bohórquez, Rajesh Mani et al.
· Communications Biology · 0 citations