Author

Toshiharu Ninomiya

3 papers indexed here

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Open access Aug 2026

Deep learning-derived magnetic resonance imaging masseter muscle volume is associated with oral impairment and cognitive frailty in older Japanese adults.

BACKGROUND AND OBJECTIVES The masseter muscle is associated with oral impairment and age-related functional decline, yet scalable and objective indicators remain limited in epidemiological studies. We developed a convolutional neural network (CNN) to segment the masseter muscle on T1-weighted magnetic resonance images...

Li-Ying Chen, B. Thyreau, Y. Tatewaki et al. · Experimental Gerontology · 0 citations

Sep 2026

Implications of urinary albumin-to-creatinine ratio for subsequent kidney function decline and kidney-related outcomes in patients hospitalized for worsening heart failure: Insights from the JROADHF-NEXT registry.

BACKGROUND Albuminuria is a well-established marker of kidney damage. However, its association with subsequent kidney function and outcomes in patients with heart failure remains unclear. METHODS We utilized data from JROADHF-NEXT, a prospective, nationwide registry enrolling patients hospitalized for heart failure....

Y. Akama, Y. Singh, T. Nakade et al. · Journal of Cardiac Failure · 0 citations

Open access Sep 2026

Association Between Changes in Serum N-Terminal Pro B-Type Natriuretic Peptide Levels and All-Cause and Cause-Specific Mortality　- The Hisayama Study.

BACKGROUND Few epidemiological studies have investigated the association between changes in serum N-terminal pro B-type natriuretic peptide (NT-proBNP) and mortality in the general Asian population. METHODS AND RESULTS We followed 2,703 community-dwelling Japanese residents aged ≥40 years who had serum NT-proBNP conc...

Asahi Kato, Emi Oishi, Akihiro Maezono et al. · Circulation Journal · 0 citations

Toshiharu Ninomiya

Deep learning-derived magnetic resonance imaging masseter muscle volume is associated with oral impairment and cognitive frailty in older Japanese adults.

Implications of urinary albumin-to-creatinine ratio for subsequent kidney function decline and kidney-related outcomes in patients hospitalized for worsening heart failure: Insights from the JROADHF-NEXT registry.

Association Between Changes in Serum N-Terminal Pro B-Type Natriuretic Peptide Levels and All-Cause and Cause-Specific Mortality - The Hisayama Study.

Association Between Changes in Serum N-Terminal Pro B-Type Natriuretic Peptide Levels and All-Cause and Cause-Specific Mortality　- The Hisayama Study.