Author

Toshihisa Maeshima

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Open access Aug 2026

ADP-Bound States of Cytoplasmic Dynein: Cryo-electron Microscopy Reveals a Two-Step Post-Power-Stroke Transition and Roles of Regulatory ATPase Sites.

These findings provide a mechanistic model in which coordinated conformational dynamics across multiple ATPase sites govern dynein's chemomechanical cycle and suggest a dynamic equilibrium between two ADP-bound states.

Hiroshi Imai, R. Kanazawa, Toshihisa Maeshima et al. · Journal of Molecular Biology · 0 citations