Identification of Key Amino Acid Residues in the Adenylation Domains of Polymyxin Synthetase Responsible for l‑Threonine Adenylation in Paenibacillus polymyxa NBRC3020
In nonribosomal peptide synthetase (NRPS) research, expanding our understanding of the relationship between active-site amino acid residues in adenylation (A) domains and their adenylation activity and substrate specificity remains essential, as detailed biochemical characterization is still limited. In this study, we...