Open access
Aug 2026
Disruption of de novo fatty acid biosynthesis rewires cellular lipid metabolism toward mTOR-associated compensatory fatty acid uptake
Integrative multi-omics analyses in EL4 T cells reveal unrecognized mechanisms of lipid metabolic adaptation and highlight a regulatory network that coordinates fatty acid uptake in response to impaired lipid synthesis.
Takeru Endo, T. Kanno, R. Konno et al.
· Scientific Reports · 0 citations