Touseef Nawaz

Biofluid-Programmed Biological Identity of Nanocarriers: Consequences for Drug Targeting and Reproducible Delivery.

Nanocarriers are commonly designed and evaluated based on their physicochemical properties, including size, morphology, surface charge, composition, ligand density, drug loading, and release behavior. After administration, however, nanocarrier surfaces are rapidly remodeled by proteins, lipids, metabolites, enzymes, mu...

Atorvastatin-loaded HPMC/Eudragit composite hydrogel film dressings: physicomechanical properties, sustained release, and wound-repair performance.

Hydroxypropyl methylcellulose (HPMC)/Eudragit L100 composite hydrogel film dressings were developed for the localized and sustained delivery of atorvastatin to excisional wounds. Solvent-cast formulations containing different HPMC/Eudragit ratios were screened for swelling, mass loss, and tensile strength, and the opti...

Pathway-specific mechanisms, therapeutic applications, and toxicodynamic profile of acriflavine in cancer: a comprehensive review.

Delivering Degradation: Nanomedicine and Programmable Proximity Platforms for Targeted Protein Degradation

This critical review is an outline of all lipid, polymeric, inorganic, biomimetic, targeted, activatable, and self-assembling delivery systems for TPD, and assess compositional considerations, in vitro and in vivo evidence, challenges for translation, and clinical endpoints required to support delivery-enabled degradat...