In Silico Target Fishing, Molecular Docking, and ADMET Profiling Suggest 6-Shogaol as a Potential Lead Compound Targeting ALOX5 in Insulin Resistance
L. Sonya, Viega De, Ariesta Supusepa et al.
· 0 citations
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Open access
Sep 2026
Target Fishing and Molecular Docking Study Identify 6-Shogaol as Potential Agent for Insulin Resistance Overcoming through ALOX5 Modulation
Insulin resistance underlies major metabolic disorders and is driven by chronic low-grade inflammation and oxidative stress that impair insulin signalling in peripheral tissues. Natural compounds with anti-inflammatory properties represent promising strategies to modulate this pathological axis, yet the molecular targe...
Laura Sonya Viega De Ariesta Supusepa, Triani Hertiani, Soni Siswanto
· Majalah Farmaseutik · 0 citations