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Trini Nguyen

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Open access Sep 2026

Recurrent deletions and regulatory disruption of the Y chromosome in cancer

High-coverage whole-genome sequencing, large-scale transcriptomics, and eQTL are used to map male cancer cell lines, revealing a region-specific LOY landscape with recurrent euchromatic deletions affecting protein-coding genes and non-coding elements and motivating validation in primary tumor cohorts.

Trini Nguyen, Aditi Kuchi, Hong-Yu Liu et al. · 0 citations

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