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Author

Tristan D. Clemons

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Open access Jul 2026

Leveraging Supramolecular Polymers to Induce the Targeted Protein Degradation of α-Synuclein

This work focused on adding modularity and dynamic capability to this classical model by leveraging a multivalent macromolecular approach to TPD, where peptide amphiphiles were designed to self-assemble into high-aspect-ratio supramolecular nanofibers and present peptide epitopes on the surface of the fibers to target...

Windfield S. Swetman, Malay Mondal, Ashe M. Davis et al. · 0 citations
Open access Aug 2026

Amphiphilic Lipid–Polymer Triblock Architectures as Nanocarriers for Therapeutic Delivery

Results indicate that NPs within the therapeutic size window (<200 nm) and with near-neutral surface charges meet key criteria for systemic delivery, and modulation of hydrophilic block identity produced distinct NP surface chemistries that appear to influence cellular uptake behavior.

Angel M. Weather, Penelope E. Jankoski, Allison Rattay et al. · 0 citations

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