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Tristan Wagner

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Review Open access Oct 2026

The DAMP Awakens: The Role of Heme and Heme Oxygenase-1 in Organ Transplantation

Ischemia-reperfusion injury (IRI) determines early and delayed graft function and long-term allograft survival in solid organ transplantation and is one determinant of outcome that remains modifiable in the operating room. Cell-free heme, a Danger-Associated Molecular Pattern (DAMP), is liberated from hemoproteins as a...

Tristan Wagner, M. Thomas, L. Otterbein · 0 citations

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