APPLICATION OF QUALITY BY DESIGN IN RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR EFAVIRENZ IN BULK AND TABLET DOSAGE FORM
Objective: This study focused on designing and validating a reliable and efficient Quality by Design assisted RP-HPLC analytical procedure for efavirenz in bulk and tablet dosage form. Methods: The significant analytical variables (CMPs) were optimized by using Central Composite Design, analytical variables; including...