Tsholofelo L. Malaka

Evaluation of residual disease detection by 10-colour flow cytometry using Navios, Navios EX and Kaluza C versus real-time quantitative polymerase chain reaction

Background: Measurable residual disease (MRD) analysis is critical in acute lymphoblastic leukaemia (ALL) management protocols. Real-time quantitative polymerase chain reaction (RT-qPCR) is the accepted gold standard in MRD testing. Multi-parameter flow cytometry has emerged as a comparative testing modality. We evalua...