Exploring the Potential Mechanism of Isoliquiritigenin in the Treatment of Osteoarthritis through Integrated Network Pharmacology, Molecular Docking, and Experimental Validation.
INTRODUCTION Osteoarthritis (OA) is a prevalent and chronic joint disease characterized by progressive cartilage degeneration and chronic inflammation. Isoliquiritigenin (ISL), a bioactive flavonoid derived from licorice, has demonstrated significant anti-inflammatory potential in various diseases. However, its specifi...