Author

Tushar Patel

2 papers indexed here

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Open access Aug 2026

Engineered Natural Killer Cell Derived-Extracellular Vesicles: An Acellular Immunotherapy with Cytotoxic Effects in SNU-1079 Human Cholangiocarcinoma Cells

The use of natural killer (NK) cells for the treatment of solid tumors such as cholangiocarcinoma has been hindered by challenges related to cell production, persistence and trafficking, as well as by reduced efficacy within an immunosuppressive tumor microenvironment. Antitumor immunity can be reduced by the interacti...

Piyush Gondaliya, Dylan A. Zinn, A. A. Sayyed et al. · Molecular Pharmaceutics · 0 citations

Jul 2026

Abstract A033: Integrating cell-SELEX and deep learning method for discovery of high-affinity aptamers targeting cholangiocarcinoma

Cholangiocarcinoma (CCA) is an aggressive biliary malignancy with poor prognosis and limited treatment options, underscoring the need for targeted RNA-based therapeutic strategies. Though DNA- aptamers could be one of the promising targeted ligands, conventional enrichment-driven selection often fails to reliably ide...

Sourav Pal, Julia Driscoll, Brandon A. Wilbanks et al. · Clinical Cancer Research · 0 citations