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Open access Sep 2026

Striatal Dopaminergic Reserve Shapes the Longitudinal Impact of Peripheral Immune Activation on Motor Progression in Parkinson's Disease.

BACKGROUND Peripheral immune dysregulation has been implicated in Parkinson's disease (PD) progression, but whether motor deterioration reflects accelerated nigrostriatal degeneration or residual dopaminergic reserve remains unclear. OBJECTIVES To examine whether baseline and time-varying neutrophil-to-lymphocyte rat...

O. Kahveci, U. Ay, T. Demiralp · 0 citations
Case report Sep 2026

Expanding the adult spectrum of TUBB4A disease: a spasticity–tremor phenotype with network imaging correlates

A Turkish family with a novel TUBB4A nucleotide variant with late-onset spasticity, tremor and mild frontal executive dysfunction is characterized, suggesting distributed structural abnormalities despite relatively mild clinical expression.

E. Hacılar, B. Samancı, U. Ay et al. · 0 citations

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