Author

U. Broeckel

3 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Sep 2026

Evaluation of functional annotation-informed and ancestry-specific polygenic risk scores for ischemic stroke

Functional annotation-informed PRSs and expanded reference panels modestly improved prediction, particularly among EA participants, and limited performance among AA participants underscores the need for larger, more diverse genomic datasets and integrative models incorporating genetic, clinical, lifestyle, and social d...

N. Armstrong, V. Srinivasasainagendra, Amit Patki et al. · Frontiers in Bioinformatics · 0 citations

Open access Jul 2026

Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed.

This work fine-mapped UK Biobank-derived genome-wide association study (GWAS) signals from 164 traits and identified e/sQTL colocalizations for 10,611 GWAS signals, including 7096 that colocalize with secondary e/sQTLs.

Peter Orchard, T. Blackwell, L. Kachuri et al. · Science · 0 citations

Open access Jul 2026

Improving performance of polygenic risk scores for hypertension across two ancestry groups

Both annotations and the updated LD panel improved the scores in both ancestry groups, but did not make the scores more equitable across the groups.

Marguerite R. Irvin, V. Srinivasasainagendra, N. Armstrong et al. · PLoS ONE · 0 citations