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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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U. Germann

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Open access Oct 2026

Targeting Pro-Inflammatory Interleukin-1 Beta Signaling to Modulate Neuroinflammatory Processes Associated with Cognitive Decline in Dementia with Lewy Bodies

Highlights What are the main findings? The oral p38α kinase inhibitor neflamapimod potently (EC50 ~6 nM) inhibits IL-1β-induced IL-6 and IL-8 production from human peripheral blood mononuclear cells. In clinical studies, neflamapimod reduces CSF levels of IL-6 and IL-8 in patients with early Alzheimer’s disease, and in...

John J. Alam, U. Germann, P. Maruff · 0 citations

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