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Author

U. Heilbronner

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Open access Sep 2026

Epigenetic age acceleration is associated with brain connectivity changes and the risk of major depression after trauma

Background: Major depressive disorder (MDD) is associated with brain dysfunction and age-related diseases. Epigenetic clocks based on DNA methylation patterns estimate biological aging and aim to predict morbidity and mortality. Although MDD has been linked to epigenetic age acceleration (EAA) cross-sectionally, it is...

A. Navarro-Flores, Hazel Milla, S. Linnstaedt et al. · 0 citations
Open access Aug 2026

Genomic dimensions deconstruct the clinical heterogeneity of bipolar disorder

Bipolar disorder’s genetic architecture appears hierarchical—a general liability resolving into dimensions of course and comorbidity, beyond subtypes, beyond subtypes.

Tracey van der Veen, M. Tesfaye, J. M. K. Yang et al. · 0 citations
Open access Jul 2026

Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders

BPD showed the strongest positive genetic correlations with GWAS of post-traumatic stress disorder, depression, attention deficit hyperactivity disorder, antisocial behavior, antisocial behavior, and measures of suicide and self-harm.

F. Streit, S. Awasthi, Alisha S. M. Hall et al. · 1 citation

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