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Open access Oct 2026

Contribution of maternal and fetal genetics to fetal weight throughout pregnancy and at birth

Background: Both fetal and maternal genomes contribute to birthweight, but the timing and relative magnitude of their effects during gestation remain unclear. Polygenic risk scores (PRSs), constructed from genome-wide association studies (GWAS), capture the cumulative influence of common birthweight-associated variants...

F. Cates, O. Wootton, J. X. Kiley et al. · 0 citations
Open access Sep 2026

Maternal immune gene expression trajectories and dynamic genetic regulation throughout pregnancy

Pregnancy involves profound changes to maternal immunity throughout gestation to simultaneously tolerate the fetus and protect both mother and baby from infection. Dysregulation of this process can lead to pregnancy complications and adverse outcomes. However, how the maternal peripheral immune system adapts throughout...

S. Hoffman, K. Burnham, E. Cook et al. · 0 citations

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