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Author

Ulrike Naumann

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Open access Aug 2026

The Hsd17b13P260S patient variant knock-in male mouse model provides translational insights into HSD17B13 biology

Summary Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent liver disease that can progress to metabolic dysfunction-associated steatohepatitis (MASH), a condition marked by inflammation and fibrosis that increases the risk of cirrhosis, liver failure, and hepatocellular carcinoma...

C. Slabber, Felina Lenkeit, Kerri Grove et al. · 0 citations
Open access Aug 2026

Long-read target enrichment sequencing for rAAV integration site analysis in engineered clones with targeted viral insertion

Together, the engineered clonal controls and optimized LR-TES provide reference material and a technical framework supporting rAAV ISA in safety evaluation, particularly when high structural resolution and specificity are needed to interpret predominant integration events.

Erica Coratella, Myriam Lemmens, Mevion Oertli et al. · 0 citations

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