Uma Sthanu

Paired RNA profiling of circulating small extracellular vesicles links survival in ALS to reactive glial - vascular programs

Circulating RNA can capture molecular variation associated with amyotrophic lateral sclerosis (ALS) progression, but biofluid heterogeneity makes biologically organized signals difficult to recover. Here, we paired microRNA (miRNA) and messenger RNA (mRNA) profiles from glutamate–aspartate transporter (GLAST)-positive...