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Author

Umayal Sivagnanalingam

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Sep 2026

Abstract B115: Divergent T cell exhaustion dynamics in periphery versus tumor during neoadjuvant chemotherapy for pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related death in the United States, with a five-year survival rate of 13%. Neoadjuvant therapy (NAT) is thought to reshape anti-tumor immunity, but its effects on circulating T cell composition/exhaustion and how this relates to intratum...

Umayal Sivagnanalingam, Renee R. Anderko, C. Arora et al. · 0 citations

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