Translational Challenges in Cartilage Regeneration for Knee Osteoarthritis: Bridging Clinical Guidelines and Animal Model Evidence
Knee osteoarthritis (OA) is a whole-joint degenerative disorder in which cartilage loss, subchondral bone remodeling, synovial inflammation, and biomechanical dysfunction restrict durable regenerative repair. This systematic translational review compared current guideline-based management of knee OA and cartilage injur...