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Urja R. Kamdar

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Open access Aug 2026

An FGF21-IGFBP1 tumor-liver relay drives musculoskeletal defects in colorectal cancer cachexia

Colorectal cancer (CRC) is frequently accompanied by cachexia, a wasting syndrome characterized by progressive loss of muscle and bone that worsens physical function and survival. Although liver dysfunction is increasingly recognized in cachexia, whether tumor-induced liver signaling contributes directly to musculosk...

J. Huot, Urja R. Kamdar, Caleb J. Gammon et al. · 0 citations

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