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Urs F. Greber

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Open access Sep 2026

Adenovirus early proteins E1A and E3-19K reveal separable regulatory states of the ER stress sensor IRE1a.

These findings show that canonical IRE1a activation hallmarks can be mechanistically separated during viral infection, revealing distinct AdV-regulated IRE1a activation states with discrete upstream and downstream signaling outputs.

Debkanya Sengupta, S. Srivastava, Fedor Bezrukov et al. · 0 citations

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