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Uzair Khalid²

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Review Open access Jul 2026

The Polygenic Risk Score in Clinical Pharmacy: From Genomic Architecture to Precision Drug Therapy: A Narrative Review

Background: Precision medicine increasingly relies on polygenic risk scores (PRS) to predict drug efficacy, safety, and therapeutic variability. Traditional monogenic pharmacogenetics, focused on individual gene variants, explains only 20-40% of drug response variation, leaving substantial "missing heritability." Polyg...

Irma Umar¹, Uzair Khalid², Sanwal Iqbal² et al. · 0 citations

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