AIM
The present research work aims to synthesize and explore the in vitro α-glucosidase inhibition potentials of DHA-salicylaldehyde-chalcone endowed 1,2,3-triazoles to counter diabetes mellitus.
MATERIALS AND METHODS
A series of DHA-salicylaldehyde-chalcone endowed 1,2,3-triazole hybrids (4a-4l) was synthesized and...
Anshul Grover, V. Asati, Jayant Sindhu et al.· Future Medicinal Chemistry· 0 citations
As the first member of the receptor tyrosine kinase family, epidermal growth factor (EGFR) has been linked to human cancers through numerous lines of evidence. Research on EGFR has also led to the development of several key theories regarding cancer progression. Through a vast array of paracrine loops, each of which...
Ankur Vaidya, Shweta Jain, B. Kumar et al.· ChemistrySelect· 0 citations
The hybrid AT5 may be used as potential lead compound after necessary structural modifications after necessaryStructural modifications in adamantane-appended 1,2,3-triazole hybrid conjugates.
Aman Ragshaniya, V. Asati, Jayant Sindhu et al.· Future Medicinal Chemistry· 1 citation
This review focuses on the AI-based approaches for target discovery, virtual screening, molecular generation, lead optimization, retro-synthesis, and structural modeling while also addressing issues of dataset bias, reproducibility, and real-world applicability.
