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Author

V. Bdzhola

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2 papers indexed here

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Open access Oct 2026

Inhibitors of Mycobacterium tuberculosis methionyl-tRNA synthetase are sensitive to the mutations E24A and L293A in aminoacyl-adenylate binding site

The objective of this study was to obtain Mycobacterium tuberculosis methionyl-tRNA synthetase (MetRS) mutant forms E24A and L293A and investigate the efficiency of M. tuberculosis MetRS inhibitors toward these mutant forms in order to predict binding mechanisms. The recombinant mutant M. tuberculosis MetRS E24A and L2...

G. Volynets, Mariia O. Usenko, O. Gorbatiuk et al. · 0 citations
Open access Oct 2026

Discovery and Biological Characterization of 1-[4-(2-Difluoromethoxyphenyl)-5-methylthiazol-2-yl]-3-(naphthalen-1-yl)urea (DFMNTU): A Novel Thiazolyl-Urea Chemotype Targeting Yellow Fever Virus and Host Casein Kinase 2 (CK2).

Yellow fever virus (YFV) is a re- emerging mosquito- borne flavivirus that causes severe hemorrhagic fever with high case- fatality rates. Due to vaccine contraindications, incomplete immunization coverage, and the absence of approved specific antivirals, host- directed drug discovery targeting cellular machinery explo...

A. Demchenko, Artur Martynov, G. Volynets et al. · 0 citations

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