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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

V. Blumenberg

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2 papers indexed here

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Open access Aug 2026

Pre-treatment T cell features and immune-milieu characteristics shape treatment-induced exhaustion and resistance to Blinatumomab in B-cell acute lymphoblastic leukemia

Background Blinatumomab (Blina), a CD19×CD3 bispecific T cell engager, is approved for the treatment of B-cell precursor acute lymphoblastic leukemia (BCP-ALL), yet resistance remains a major challenge and the mechanisms driving treatment failure remain poorly understood. Methods To define the immunological determinant...

Francesco Corrado, V. Blumenberg, Maryam Kazerani et al. · 0 citations
Sep 2026

Rational Engineering of Notch1 Signaling to Boost the Proliferation of CD19-BBζ CAR-T.

CAR T-cells targeting CD19 have revolutionized the treatment of relapsed/refractory B-cell malignancies. However, approximately 50% of patients relapse. Patient-derived data indicates that CD19+ relapse is linked to poor CAR T-cell proliferation and/or persistence. We aimed to improve CD19-CAR T-cell survival by manipu...

M. Phillips, F. Birocchi, Felix Korell et al. · 0 citations

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