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Open access Sep 2026

The Pentose Phosphate Pathway Regulates Myelo-Lymphoid Lineage Specification

Following infection, hematopoietic stem and progenitor cells (HSPCs) support immunity by increasing the rate of innate immune cell production but the metabolic cues that guide this process are unknown. To address this question, we combined in situ RNA barcoding and metabolomics approaches to perform metabolic state-fat...

J. Cosgrove, A. Donada, A. Lyne et al. · 0 citations
Open access Sep 2026

BOTANIC-1: a series of long-context plant genomic foundation models in the agentic era

The Botanic1 family of gLMs designed for plant research is presented, which operates reliably on sequences from hundreds of base pairs up to 128 kbp, and integrates Botanic1 as a specialised genomic layer callable by a generalist large language model (LLM) agent, illustrating how such hybrid systems could accelerate pl...

A. Barozet, V. Cabeli, Jean Ogier du Terrail et al. · 0 citations

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