Alterations in serum zinc, copper, and selenium levels in children with drug-resistant epilepsy: A systematic review and meta-analysis.
BACKGROUND Drug-resistant epilepsy (DRE) affects around one-third of children with epilepsy and is associated with high morbidity and mortality. Trace elements such as zinc (Zn), copper (Cu), and selenium (Se) play important roles in neuronal excitability, oxidative stress regulation, and enzymatic antioxidant defense....