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V. Costa

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Open access Sep 2026

Next-generation CAR-T therapy for malignant brain tumors: latest updates from the 2026 AACR Annual Meeting

The 2026 AACR Annual Meeting showcased rapid progress in chimeric antigen receptor (CAR) T-cell therapy for malignant brain tumors. This correspondence synthesizes 12 clinical and translational abstracts addressing early efficacy, resistance mechanisms, target discovery, and next-generation engineering. Phase I studies...

V. Costa, S. Rabenhorst, F. P. Mesquita · 0 citations
Review Open access Aug 2026

Antibody-drug conjugates and beyond in platinum-resistant ovarian cancer: A comprehensive review of emergent strategies

Continued translational research is therefore essential to identify predictive biomarkers and to optimize novel combination strategies to overcome resistance, as well as the integration of dynamic biomarkers and quantitative tools to define optimal treatment sequencing and improve patient outcomes in this challenging d...

M. Noronha, L. F. Costa de Almeida, V. Costa et al. · 0 citations

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