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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

V. de Crécy-Lagard

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Open access Sep 2026

Pyridoxal-phosphate-dependent biosynthesis of aminovaleramide by AvaS in tRNA.

In eubacteria, decoding of isoleucine codon AUA requires a specialized tRNA (tRNAIle2) modified with lysidine (k2C) at the anticodon wobble position (C34), which switches decoding specificity from methionine (AUG) to isoleucine (AUA). Recently, aminovaleramide cytidine (ava2C) was discovered at the same tRNA position i...

Jing-Jing Sun, Jun-Zhou Wu, Yi-Feng Yuan et al. · 0 citations
Open access Aug 2026

Quantitative RNA modification mapping by mass spectrometry with isobaric tags and nucleobase fragment analysis

The authors develop proteomics-style, RNA-specific isobaric tandem mass tags for quantitative RNA modification mapping by mass spectrometry, revealing condition-dependent changes and interdependencies among modification pathways.

Jun-Zhou Wu, Jing-Jing Sun, Yi-Feng Yuan et al. · 0 citations
Open access Jul 2026

Deciphering the Streptococcus mutans essentialome: multi-omic resolution of hypothetical genes and identification of a functional RocS equivalent

A critical molecular checkpoint is discovered that acts as a physical anchor, linking the bacterial chromosome to the cell envelope to ensure that chromosome replication is synchronized with cell division, and a single mutation in the replication machinery can fully bypass the loss of this anchor.

Courtney Dover, Kipa Tamrakar, Bikash Dwivedi et al. · 0 citations

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