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Author

V. Di Liberto

3 papers indexed here

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Open access Aug 2026

Behavioral and spectral electroencephalographic biomarkers of epileptogenesis, disease progression, and drug resistance in a longitudinal lithium-pilocarpine model of temporal lobe epilepsy.

Temporal lobe epilepsy (TLE) is linked to progressive alterations in brain network dynamics, leading to behavioral comorbidities and emergence of drug resistance; yet the underlying mechanistic and synaptic substrates remain incompletely understood. Here, we performed longitudinal phase-specific characterization of net...

Giulia Urone, Nicolò Ricciardi, M. Scordino et al. · 0 citations
Open access Aug 2026

Longitudinal 1H NMR metabolomics of serum in a chronic temporal lobe epilepsy model reveals systemic metabolic remodeling

The convergence of the metabolic profiles of drug-sensitive and drug-resistant animals suggests that the systemic effects of chronic epilepsy and phenobarbital treatment dominate the serum metabolome, potentially masking subtle molecular signatures associated with drug resistance.

Veronica Ghini, Lucrezia Cosottini, M. Scordino et al. · 0 citations

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